This research is quantitative descriptive by using SPSS version 23. This study aims to determine how the application of Problem-Based Learning through the cases on International Accounting learning. Population and sample in this study amounted to 34 students, who responded agree and do not agree on what through a questionnaire based on research Khanova et al,(2015). The results showed that more than 50% responded agreed with the model of Problem-Based Learning in International Accounting learning in particular cases, for enhancing learning. Learning is a process of motivation in obtaining the knowledge, skills, habits and behavior (Gagne & Briggs, 1979). Application of Problem-Based Learning through the cases on International Accounting learning can improve student learning. Problem-Based Learning is a teaching and learning approach of Student-Centered Learning in which students are directed to develop themselves in learning (Beacham & Shambaugh 2007). Problem-Based Learning is a learning model for students to be able to collaborate and explore to solve the problem (Skowron, 2006; Torp & Sage, 2002).